The Human Endocannabinoid System

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It is known to produce side effects like electrolyte imbalance, rash, fatigue, light sensitivity, and low blood pressure. Studies have not demonstrated the propensity for amoxicillin to inhibit the production of CYP3A4, meaning it is unlikely to produce an adverse reaction with CBD. Taking CBD in conjunction with simvastatin may decrease the drug’s effectiveness, prolong its side effects, and possibly lead to medication toxicity due to the drug’s prolonged presence in the bloodstream.

It is also prescribed to patients suffering from coronary artery diseases as a safeguard against stroke, heart attack, and chest pain. It may also cause diarrhea, constipation, muscle pain, fatigue, gas, heartburn, and headaches.

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It can also be prescribed to treat bronchitis, pneumonia, and certain bacterial sexually transmitted infections. It may produce the side effects of vomiting, gas, bloating, and diarrhea.

The generic form of the drug Norvasc, amlodipine is a calcium channel blocker. It is prescribed to prevent chest pain and treat high blood pressure. It can cause headaches, dizziness, chest pain, and swollen extremities. Lipitor is another statin, commonly prescribed to patients suffering from high cholesterol.

Hydrochlorothiazide is not metabolized by CYP3A4, nor is it known to inhibit or stimulate the production of the enzyme. This means it is not likely to produce an adverse reaction with CBD. It is prescribed to patients suffering from high blood pressure.

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The generic version of the drug Glucophage, metformin is used to treat type 2 diabetes. Common side effects include gas, nausea, bloating, reduced appetite, and diarrhea.

Unlike its relative erythromycin, azithromycin only metabolizes weakly with CYP450 enzymes and is not known to either stimulate or inhibit the production of CYP450 enzymes. There is little or no indication that azithromycin will interact adversely with CBD. The antibiotic azithromycin is usually prescribed to treat throat, sinus, and ear infections.

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